| 肖彩琴,朱丽君.化学通报,2023,86(8):995-1004,959. |
| 2-取代苯并噻吩类化合物合成研究进展 |
| Progress on the Syntheses of 2-Substituted Benzo[b]thiophenes |
| 投稿时间：2022-12-26 修订日期：2023-01-17 |
| DOI： |
| 中文关键词: 苯并噻吩类化合物 合成 |
| 英文关键词:Benzo[b]thiophenes, Synthesis |
| 基金项目:国家自然科学基金项目(21762040)和2020年甘肃省高等学校创新能力提升项目(2020B-379)资助 |
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| 中文摘要: |
| 2-取代苯并噻吩广泛的存在于天然产物中，独特的分子结构使其表现出了较高的药理和生物活性，常被用于药物化学和材料化学中。已有多种具有苯并噻吩骨架药物用于临床，故具有极高的研究价值。本文结合国内外学者对这方面的相关研究，重点对2-苯基苯并噻吩、2-酰基苯并噻吩和2-氨基苯并噻吩类化合物的合成方法进行了综述。 |
| 英文摘要: |
| 2-substituted benzo[b]thiophenes are is widely found in natural products. Owing to their unique molecular structure, these compounds always exhibit high pharmacological and biological activities and are frequently employed as a key structural unit in pharmaceutical chemistry and material chemistry. A variety of drugs that encompass benzo[b]thiophene structural unit have been used in clinic, addressing their high research value. This paper aimed to summarize the recent developments on the synthetic methods of 2-phenylbenzo[b]thiophenes, 2-acetylbenzo[b]thiophenes and 2-aminobenzo[b]thiophenes. |
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